loading...| Preferred Name |
Sulfonamide Anti-Infective Agent |
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29739 |
| ALT_DEFINITION |
A type of antibiotic used to treat infection. |
| code |
C29739 |
| DEFINITION |
A class of natural or synthetic sulfanilamide derivatives with antibacterial activity. Sulfonamides are structural analogs of para-aminobenzoic acid (essential for microbial folate synthesis). Sulfonamides inhibit bacterial metabolism by competing with PABA for dihydropteroate synthase, thereby resulting in disruption of folic acid metabolism and ultimately DNA synthesis. |
| FULL_SYN |
Sulfonamides sulfonamide sulfa drug Sulfonamide Anti-Infective Agent |
| label |
Sulfonamide Anti-Infective Agent |
| Legacy Concept Name |
Sulfonamide_Anti-infective_Agent |
| NCI_META_CUI |
CL557618 |
| Preferred_Name |
Sulfonamide Anti-Infective Agent |
| prefixIRI |
Thesaurus:C29739 |
| prefLabel |
Sulfonamide Anti-Infective Agent |
| Semantic_Type |
Chemical Viewed Functionally |
| subClassOf |
| Delete | Mapping To | Ontology | Source |
|---|---|---|---|
| There are currently no mappings for this class. | |||