Preferred Name

Interleukin 3 Receptor

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C39273

code

C39273

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142799

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142800

Contributing_Source

CTRP

DEFINITION

Heterodimeric human Interleukin 3 Receptor is composed of 378-aa 43-kDa (precursor) Interleukin 3 Receptor Alpha and GM-CSF/IL-3/IL-5 Receptor Common Beta-Chain. IL3RA is a type I membrane protein with a box 1 motif for JAK interaction/activation and a WSXWS motif for protein folding, intracellular transport, and cell-surface receptor binding. Receptor binding to IL3 depends on the signal transducing beta subunit, common to the high affinity IL3-, IL5- and GM-CSF receptors. (NCI)

Display_Name

Interleukin 3 Receptor

FULL_SYN

IL-3 Receptor

Interleukin-3 Receptor

Interleukin 3 Receptor

IL3 Receptor

label

Interleukin 3 Receptor

Legacy Concept Name

Interleukin-3_Receptor

Preferred_Name

Interleukin 3 Receptor

prefixIRI

Thesaurus:C39273

prefLabel

Interleukin 3 Receptor

Semantic_Type

Receptor

Amino Acid, Peptide, or Protein

UMLS_CUI

C0080096

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C21176

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