loading...| Preferred Name |
CTLA4 wt Allele |
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C51345 |
| code |
C51345 |
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977 |
| Contributing_Source |
CTRP |
| DEFINITION |
Human CTLA4 wild-type allele is located within 2q33 and is approximately 6 kb in length. This allele, which encodes cytotoxic T-lymphocyte protein 4, is involved in signal transduction and T-cell regulation. Variant alleles generated from mutations in the gene, have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases. |
| Display_Name |
CTLA4 wt Allele |
| EntrezGene_ID |
1493 |
| FULL_SYN |
CTLA4 CELIAC3 CTLA-4 CTLA4 wt Allele CD152 Gene ALPS5 Cytotoxic T-Lymphocyte Associated Protein 4 wt Allele GRD4 CD152 Cytotoxic T Lymphocyte-Associated 4 Gene CD CTLA-4 Gene Cytotoxic T-Lymphocyte Protein 4 Gene CD152 Antigen Gene Cytotoxic T-Lymphocyte-Associated Protein 4 Gene Cytotoxic T-Lymphocyte-Associated Serine Esterase-4 Gene GSE IDDM12 Cytotoxic T-Lymphocyte-Associated Antigen 4 Gene CTLA4-TM |
| GenBank_Accession_Number |
NM_005214 |
| Gene_Encodes_Product |
Cytotoxic T-Lymphocyte-Associated Protein 4 |
| GO_Annotation |
integral to plasma membrane immune response |
| label |
CTLA4 wt Allele |
| Legacy Concept Name |
CTLA4_wt_Allele |
| OMIM_Number |
123890 |
| Preferred_Name |
CTLA4 wt Allele |
| prefixIRI |
Thesaurus:C51345 |
| prefLabel |
CTLA4 wt Allele |
| Semantic_Type |
Gene or Genome |
| UMLS_CUI |
C1705969 |
| subClassOf |
| Delete | Mapping To | Ontology | Source |
|---|---|---|---|
| There are currently no mappings for this class. | |||