loading...| Preferred Name |
Multikinase Inhibitor SAR103168 |
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C88278 |
| code |
C88278 |
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157712 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C177537 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157711 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424 |
| Contributing_Source |
CTRP GDC |
| DEFINITION |
A multikinase inhibitor with potential antineoplastic activity. Upon intravenous infusion, multikinase inhibitor SAR103168 may, through the inhibition of multiple kinases, inhibit the phosphorylation and activation of signal transducer and activator of transcription 5 (STAT5). STAT5, a protein often upregulated in cancer cells, plays a key role in signal transduction pathways and the suppression of apoptosis. |
| Display_Name |
Multikinase Inhibitor SAR103168 |
| FULL_SYN |
Multikinase Inhibitor SAR103168 SAR103168 |
| Is_Value_For_GDC_Property | |
| label |
Multikinase Inhibitor SAR103168 |
| Maps_To |
Multikinase Inhibitor SAR103168 |
| NCI_Drug_Dictionary_ID |
656309 |
| PDQ_Closed_Trial_Search_ID |
656309 |
| PDQ_Open_Trial_Search_ID |
656309 |
| Preferred_Name |
Multikinase Inhibitor SAR103168 |
| prefixIRI |
Thesaurus:C88278 |
| prefLabel |
Multikinase Inhibitor SAR103168 |
| Semantic_Type |
Pharmacologic Substance |
| UMLS_CUI |
C2981800 |
| subClassOf |
| Delete | Mapping To | Ontology | Source |
|---|---|---|---|
| There are currently no mappings for this class. | |||