Preferred Name

NEDD8 Activating Enzyme

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C95815

code

C95815

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142799

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142800

Contributing_Source

CTRP

DEFINITION

NEDD8 activating enzyme is comprised of NEDD8-activating enzyme E1 regulatory subunit and NEDD8-activating enzyme E1 catalytic subunit. This protein complex modifies the C-terminus of NEDD8 to regulate protein neddylation, ubiquitination and catabolism.

Display_Name

NEDD8 Activating Enzyme

FULL_SYN

NEDD8 Activating E1 Enzyme

UBA3-NAE1 E1 Enzyme

NAE

NEDD8 Activating Enzyme

NEDD8-Activating Enzyme

label

NEDD8 Activating Enzyme

Preferred_Name

NEDD8 Activating Enzyme

prefixIRI

Thesaurus:C95815

prefLabel

NEDD8 Activating Enzyme

Semantic_Type

Enzyme

Amino Acid, Peptide, or Protein

UMLS_CUI

C3272370

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C21176

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