Preferred Name

mTORC2

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C96315

code

C96315

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142799

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142800

Contributing_Source

CTRP

DEFINITION

A protein complex that is involved in both serine/threonine phosphorylation and cytoskeleton remodeling in response to cellular stress.

DesignNote

mTORC2 is comprised of serine/threonine-protein kinase mTOR, rapamycin-insensitive companion of mTOR, proline-rich protein 5, target of rapamycin complex 2 subunit MAPKAP1 and target of rapamycin complex subunit LST8. (UniProt)

Display_Name

mTORC2

FULL_SYN

TORC2

mTORC2

Rictor/TORC2

Mammalian Target of Rapamycin Complex 2

mTOR Complex 2

TOR Complex 2

Target of Rapamycin Complex 2

Rictor-mTOR

label

mTORC2

Preferred_Name

mTORC2

prefixIRI

Thesaurus:C96315

prefLabel

mTORC2

Semantic_Type

Enzyme

Amino Acid, Peptide, or Protein

UMLS_CUI

C3152112

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C21176

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