loading...| Preferred Name |
Slit Homolog 2 Protein |
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C126787 |
| code |
C126787 |
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977 |
| Contributing_Source |
CTRP |
| DEFINITION |
Slit homolog 2 protein (1529 aa, ~170 kDa) is encoded by the human SLIT2 gene. This protein is involved in the modulation of cell migration and the development of the nervous system. |
| DesignNote |
Slit homolog 2 protein is cleaved into an N-terminal fragment that contains the four leucine-rich repeats and five epidermal growth factor repeats and a C-terminal fragment that contains four epidermal growth factor repeats and the cysteine knot.. The Slit homolog 2 protein N-terminal product may repress olfactory bulb axon growth and induce dorsal root ganglia axon migration. (UniProt) Slit homolog 2 protein is a ligand for both roundabout homolog 1 and 2; it also can bind to gremlin-1. |
| Display_Name |
Slit Homolog 2 Protein |
| FULL_SYN |
Slit-2 Slit Homolog 2 Protein Slit Homolog 2 |
| label |
Slit Homolog 2 Protein |
| OMIM_Number |
603746 |
| Preferred_Name |
Slit Homolog 2 Protein |
| prefixIRI |
Thesaurus:C126787 |
| prefLabel |
Slit Homolog 2 Protein |
| Semantic_Type |
Amino Acid, Peptide, or Protein |
| Swiss_Prot |
O94813 |
| UMLS_CUI |
C1741674 |
| subClassOf |