Antibody-Dependent Cellular Cytotoxicity

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C16298

A type of immune reaction in which a target cell or microbe is coated with antibodies and killed by certain types of white blood cells. The white blood cells bind to the antibodies and release substances that kill the target cells or microbes.

C16298

The target killing of a cell depending on antibody recognition. An antibody is directed to the target by antigen-binding arms and anchors to the killer cell by an Fc receptor. The identity of the target cell varies, but it must possess surface IgG whose Fc portion is intact. The effector "killer" cell possesses Fc receptors. It may be a lymphocyte lacking conventional B- or T-cell markers, or a monocyte, macrophage, or polynuclear leukocyte, depending on the identity of the target cell. The reaction is complement-independent.

ADCC

antibody-dependent cellular cytotoxicity

Antibody-Dependent Cellular Cytotoxicity

antibody-dependent cell-mediated cytotoxicity

Antibody-Mediated Lympholysis

Antibody-Dependent Cellular Cytotoxicity

Antibody-Dependent_Cellular_Cytotoxicity

Antibody-Dependent Cellular Cytotoxicity

Thesaurus:C16298

Antibody-Dependent Cellular Cytotoxicity

Cell Function

C0003272

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17709