Histone H4

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C16686

An antigen in the core histone family and a subunit of the nucleosome complex, with a designation of H4. It can be considered as an autoantigen and is commonly associated with the autoimmune diseases systemic lupus erythematosus and rheumatoid arthritis.

C16686

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C66830

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C177537

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157711

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61410

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142799

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181169

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142800

CDISC

CTRP

GDC

Histone H4 (103 aa, ~11 kDa) is encoded by the human H4C1, H4C2, H4C3, H4C4, H4C5, H4C6, H4C6, H4C8, H4C9, H4C11, H4C12, H4C13, H4C14, H4C15, H4-16 genes. This protein plays a role in nucleating the formation of high order chromatin structures as a part of nucleosomes.

Histone H4 is encoded for by a cluster of genes that are clustered in the vicinity of 6p21.33 and all have the same SwissProt identifier.

Histone H4 is a core subunit of the eukaryotic nucleosome complex. Histones are basic nuclear proteins responsible for the nucleosome structure of chromatin. Repeating nucleosome units contain two molecules each of Histones H2A, H2B, H3, and H4 that form an octamer complex around which approximately 146 base pairs of DNA is wrapped. The nucleosome interacts with DNA between nucleosome units in mediating chromatin compaction into higher order structures.

Histone H4

HISTONE H4

Histone H4

H4

HIST1H4

Histone 1, H4

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C16687

Histone H4

Histone-H4

H4

602830

602833

Histone H4

Thesaurus:C16686

Histone H4

Amino Acid, Peptide, or Protein

P62805

C0019648

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C16687