Preferred Name

Apoptosis

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17557

ALT_DEFINITION

A form of programmed cell death triggered by internal or external signals that results in a series of characteristic morphological changes.

A type of cell death in which a series of molecular steps in a cell leads to its death. This is the body's normal way of getting rid of unneeded or abnormal cells. The process of programmed cell death may be blocked in cancer cells.

code

C17557

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61410

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C120531

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C77526

Contributing_Source

CDISC

DEFINITION

A form of programmed cell death that begins when a cell receives internal or external signals, then proceeds through a series of characteristic stages typically including rounding-up of the cell, retraction of pseudopods, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), and plasma membrane blebbing, and ends with the death of the cell.

DesignNote

Important in ontogenesis, tumorigenesis, tissue turnover, lymphocyte selection and function and hormone-induced atrophy.

FULL_SYN

Apoptotic Process

programmed cell death

apoptosis

APOPTOSIS

Programmed Cell Death

PCD

Apoptosis

label

Apoptosis

Legacy Concept Name

Apoptosis

Preferred_Name

Apoptosis

prefixIRI

Thesaurus:C17557

prefLabel

Apoptosis

Semantic_Type

Phenomenon or Process

UMLS_CUI

C0162638

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C41515

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http://purl.bioontology.org/ontology/MESH/D017209 Medical Subject Headings / 医学主题词表 LOOM