loading...| Preferred Name |
E3 Ubiquitin-Protein Transferase |
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C21254 |
| code |
C21254 |
| DEFINITION |
An ATP-dependent aminoacyltransferase that catalyzes the third step in the ubiquitination reaction via the transfer of ubiquitin from an E2 ubiquitin-conjugating enzyme to lysine residues found in the final substrate protein. |
| DesignNote |
The IUBMB has recategorized E3 ubiquitin-protein ligases as transferases (EC 2). There are 2 categories of E3 enzymes based on the structure of the active site: HECT-type (EC 2.3.2.26) and RING-type (EC 2.3.2.27). |
| FULL_SYN |
E3 Ubiquitin Ligase E3 Ubiquitin-Protein Transferase E3 Ubiquitin-Protein Ligase E3 Ubiquitin Transferase |
| label |
E3 Ubiquitin-Protein Transferase |
| Legacy Concept Name |
E3_Ubiquitin_Ligase |
| NCI_META_CUI |
CL449066 |
| Preferred_Name |
E3 Ubiquitin-Protein Transferase |
| prefixIRI |
Thesaurus:C21254 |
| prefLabel |
E3 Ubiquitin-Protein Transferase |
| Semantic_Type |
Enzyme Amino Acid, Peptide, or Protein |
| subClassOf |
| Delete | Mapping To | Ontology | Source |
|---|---|---|---|
| There are currently no mappings for this class. | |||