| Preferred Name |
ACE Inhibitor |
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C247 |
| Accepted_Therapeutic_Use_For |
Hypertension |
| ALT_DEFINITION |
A drug that is used to lower blood pressure. An ACE inhibitor is a type of antihypertensive agent. A pharmaceutical agent that inhibits angiotensin-converting enzyme (ACE), which catalyzes the conversion of angiotensin I to angiotensin II. Inhibition of ACE results in a reduction in angiotensin II and angiotensin II-induced aldosterone secretion, causing vasodilation and natriuresis. It is primarily used for the reduction of proteinuria and the treatment of hypertension. A medication that inhibits ACE, an enzyme that catalyzes the conversion of angiotensin I to angiotensin II. Inhibition of ACE results in a reduction in angiotensin II and angiotensin II-induced aldosterone secretion, causing vasodilation and natriuresis. |
| CHEBI_ID |
CHEBI:35457 |
| code |
C247 |
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C191670 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C191387 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C191200 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C118468 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C90259 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C191405 |
| Contributing_Source |
ACC/AHA NICHD PCDC |
| DEFINITION |
Any substance that inhibits angiotensin-converting enzyme (ACE), an enzyme that catalyzes the conversion of angiotensin I to angiotensin II. Inhibition of ACE results in a reduction in angiotensin II and angiotensin II-induced aldosterone secretion, causing vasodilation and natriuresis. |
| FULL_SYN |
ACE-inhibitor angiotensin-converting enzyme inhibitor ACE Inhibitor Angiotensin-Converting Enzyme Inhibitor ACE inhibitor Angiotensin-converting enzyme (ACE) inhibitor medication |
| Has_ACC-AHA_SARS2_Authorized_Value |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17998 |
| Is_PCDC_AML_Authorized_Value_For_Variable | |
| label |
ACE Inhibitor |
| Legacy Concept Name |
ACE_Inhibitor |
| Preferred_Name |
ACE Inhibitor |
| prefixIRI |
Thesaurus:C247 |
| prefLabel |
ACE Inhibitor |
| Semantic_Type |
Chemical Viewed Functionally |
| UMLS_CUI |
C0003015 |
| subClassOf |
| Delete | Mapping To | Ontology | Source |
|---|---|---|---|
| http://purl.bioontology.org/ontology/LNC/LP213629-1 | Logical Observation Identifier Names and Codes / 逻辑观察标识符名称和代码 | LOOM |