Preferred Name

Leukotriene B4 Receptor 1

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C26329

code

C26329

DEFINITION

.Leukotriene B4 receptor 1 (352 aa, ~38 kDa) is encoded by the human LTB4R gene. This protein is involved in both purine nucleotide binding and G protein-coupled receptor signaling.

DesignNote

Leukotriene B4 Receptor, encoded by the LTB4R gene, belongs to family 1 of G-protein coupled receptors. This protein is a receptor for extracellular ATP, UTP and ADP, and its activity is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. This protein may be the cardiac P2Y receptor involved in the regulation of cardiac muscle contraction through modulation of L-type calcium currents. It is also a receptor for leukotriene B4, a potent chemoattractant involved in inflammation and immune response. It is expressed at highest levels in heart, skeletal muscle and at lower levels in brain and liver, with high level of expression in lymphoid tissues. (SwissProt)

FULL_SYN

P2Y Purinoceptor 7

Leukotriene B4 Receptor 1

LTB4-R 1

Leukotriene B4 Receptor

LTB4R

Leukotriene B4 G Protein-Coupled Receptor

P2Y7

G-Protein Coupled Receptor 16

G Protein-Coupled Receptor 16

LTB4-R1

Chemoattractant Receptor-Like 1

Chemokine Receptor-Like 1

Purinoceptor P2Y7

label

Leukotriene B4 Receptor 1

Legacy Concept Name

Leukotriene-B4_Receptor

OMIM_Number

601531

Preferred_Name

Leukotriene B4 Receptor 1

prefixIRI

Thesaurus:C26329

prefLabel

Leukotriene B4 Receptor 1

Semantic_Type

Receptor

Amino Acid, Peptide, or Protein

Swiss_Prot

Q15722

UMLS_CUI

C1307920

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C18239

Delete Subject Author Type Created
No notes to display
Create New Mapping

Delete Mapping To Ontology Source
http://purl.obolibrary.org/obo/PR_000001594 Protein Ontology / 蛋白质本体 LOOM
http://purl.obolibrary.org/obo/PR_000001594 Experimental Factor Ontology / 实验性因素本体 LOOM