| Preferred Name |
Leukotriene B4 Receptor 1 |
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C26329 |
| code |
C26329 |
| DEFINITION |
.Leukotriene B4 receptor 1 (352 aa, ~38 kDa) is encoded by the human LTB4R gene. This protein is involved in both purine nucleotide binding and G protein-coupled receptor signaling. |
| DesignNote |
Leukotriene B4 Receptor, encoded by the LTB4R gene, belongs to family 1 of G-protein coupled receptors. This protein is a receptor for extracellular ATP, UTP and ADP, and its activity is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. This protein may be the cardiac P2Y receptor involved in the regulation of cardiac muscle contraction through modulation of L-type calcium currents. It is also a receptor for leukotriene B4, a potent chemoattractant involved in inflammation and immune response. It is expressed at highest levels in heart, skeletal muscle and at lower levels in brain and liver, with high level of expression in lymphoid tissues. (SwissProt) |
| FULL_SYN |
P2Y Purinoceptor 7 Leukotriene B4 Receptor 1 LTB4-R 1 Leukotriene B4 Receptor LTB4R Leukotriene B4 G Protein-Coupled Receptor P2Y7 G-Protein Coupled Receptor 16 G Protein-Coupled Receptor 16 LTB4-R1 Chemoattractant Receptor-Like 1 Chemokine Receptor-Like 1 Purinoceptor P2Y7 |
| label |
Leukotriene B4 Receptor 1 |
| Legacy Concept Name |
Leukotriene-B4_Receptor |
| OMIM_Number |
601531 |
| Preferred_Name |
Leukotriene B4 Receptor 1 |
| prefixIRI |
Thesaurus:C26329 |
| prefLabel |
Leukotriene B4 Receptor 1 |
| Semantic_Type |
Receptor Amino Acid, Peptide, or Protein |
| Swiss_Prot |
Q15722 |
| UMLS_CUI |
C1307920 |
| subClassOf |
| Delete | Mapping To | Ontology | Source |
|---|---|---|---|
| http://purl.obolibrary.org/obo/PR_000001594 | Protein Ontology / 蛋白质本体 | LOOM | |
| http://purl.obolibrary.org/obo/PR_000001594 | Experimental Factor Ontology / 实验性因素本体 | LOOM |