Preferred Name

Histone Deacetylation

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C40580

code

C40580

DEFINITION

Histone Deacetylation is the covalent post-translational enzymatic removal of acetyl group(s) from a histone protein. By exposing cationic sites on the protein that promote ionic interaction with the negatively charged DNA backbone, Histone Deacetylation induces DNA condensation and regulates genetic functions, such as transcription. (NCI)

FULL_SYN

Histone Deacetylation

label

Histone Deacetylation

Legacy Concept Name

Histone_Deacetylation

Preferred_Name

Histone Deacetylation

prefixIRI

Thesaurus:C40580

prefLabel

Histone Deacetylation

Semantic_Type

Physiologic Function

UMLS_CUI

C1156201

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C41553

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C129422

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http://purl.obolibrary.org/obo/GO_0016575 Gene Ontology / 基因本体 LOOM