loading...| Preferred Name |
sphingosine 1-phosphate signaling pathway |
| Synonyms |
S1P signaling pathway sphingosine-1-phosphate receptor signaling pathway |
| Definitions |
Sphingosine 1-phosphate (S1P), a sphingolipid metabolite, can signal intracellularly as a second messenger or extracellularly as a ligand for five G-protein-coupled receptors. The S1P pathway plays important roles in processes such as cell migration, proliferation and survival. The five receptors engage similar G-proteins but their expression varies. |
| ID |
http://purl.obolibrary.org/obo/PW_0000960 |
| created_by |
VPetri |
| creation_date |
2012-05-17T01:10:40Z |
| definition |
Sphingosine 1-phosphate (S1P), a sphingolipid metabolite, can signal intracellularly as a second messenger or extracellularly as a ligand for five G-protein-coupled receptors. The S1P pathway plays important roles in processes such as cell migration, proliferation and survival. The five receptors engage similar G-proteins but their expression varies. |
| has_obo_namespace |
pathway |
| has_related_synonym |
S1P signaling pathway sphingosine-1-phosphate receptor signaling pathway |
| id |
PW:0000960 |
| label |
sphingosine 1-phosphate signaling pathway |
| notation |
PW:0000960 |
| prefLabel |
sphingosine 1-phosphate signaling pathway |
| treeView | |
| subClassOf |
| Delete | Mapping To | Ontology | Source |
|---|---|---|---|
| http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C91667 | National Cancer Institute Thesaurus / 美国国家癌症研究所词典 | LOOM |