Pathway Ontology / 通路本体

Last uploaded: September 7, 2023
Preferred Name

CXC chemokine mediated signaling pathway

Definitions

The CXC family members are characterized by the presence of two cysteine resides separated by one amino acid. CXC and CC are the two most prominent families. This family of chemokines is also subdivided into two subgroups: the one with the ELR motif - ELR (+) and the one without - ELR(-), respectively. Generally, ELR(+) and ELR(-) members bind to distinct chemokine, G-coupled protein, receptors. The effects of their signaling is for the most part angiogenic or angiostatic, respectively.

ID

http://purl.obolibrary.org/obo/PW_0000830

created_by

VPetri

creation_date

2010-11-04T11:30:26Z

definition

The CXC family members are characterized by the presence of two cysteine resides separated by one amino acid. CXC and CC are the two most prominent families. This family of chemokines is also subdivided into two subgroups: the one with the ELR motif - ELR (+) and the one without - ELR(-), respectively. Generally, ELR(+) and ELR(-) members bind to distinct chemokine, G-coupled protein, receptors. The effects of their signaling is for the most part angiogenic or angiostatic, respectively.

has_obo_namespace

pathway

id

PW:0000830

label

CXC chemokine mediated signaling pathway

notation

PW:0000830

prefLabel

CXC chemokine mediated signaling pathway

treeView

http://purl.obolibrary.org/obo/PW_0000829

subClassOf

http://purl.obolibrary.org/obo/PW_0000829

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