| Preferred Name |
M2 macrophage |
| Synonyms |
alternatively activated macrophage |
| Definitions |
Macrophages that decrease inflammation and encourage tissue repair. M2 is the phenotype of resident tissue macrophages, and can be further elevated by IL-4. M2 macrophages produce high levels of IL-10, TGF-beta and low levels of IL-12. Tumor-associated macrophages are mainly of the M2 phenotype, and seem to actively promote tumor growth. |
| ID |
http://purl.obolibrary.org/obo/BTO_0006111 |
| created_by |
Marion, contact@brenda-enzymes.org |
| creation_date |
2017-09-26T10:37:24Z |
| definition |
Macrophages that decrease inflammation and encourage tissue repair. M2 is the phenotype of resident tissue macrophages, and can be further elevated by IL-4. M2 macrophages produce high levels of IL-10, TGF-beta and low levels of IL-12. Tumor-associated macrophages are mainly of the M2 phenotype, and seem to actively promote tumor growth. |
| has_obo_namespace |
BrendaTissueOBO |
| has_related_synonym |
alternatively activated macrophage |
| id |
BTO:0006111 |
| label |
M2 macrophage |
| notation |
BTO:0006111 |
| prefLabel |
M2 macrophage |
| treeView | |
| subClassOf |
| Delete | Mapping To | Ontology | Source |
|---|---|---|---|
| http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C123783 | National Cancer Institute Thesaurus / 美国国家癌症研究所词典 | LOOM |