Preferred Name

M2 macrophage

Synonyms

alternatively activated macrophage

Definitions

Macrophages that decrease inflammation and encourage tissue repair. M2 is the phenotype of resident tissue macrophages, and can be further elevated by IL-4. M2 macrophages produce high levels of IL-10, TGF-beta and low levels of IL-12. Tumor-associated macrophages are mainly of the M2 phenotype, and seem to actively promote tumor growth.

ID

http://purl.obolibrary.org/obo/BTO_0006111

created_by

Marion, contact@brenda-enzymes.org

creation_date

2017-09-26T10:37:24Z

definition

Macrophages that decrease inflammation and encourage tissue repair. M2 is the phenotype of resident tissue macrophages, and can be further elevated by IL-4. M2 macrophages produce high levels of IL-10, TGF-beta and low levels of IL-12. Tumor-associated macrophages are mainly of the M2 phenotype, and seem to actively promote tumor growth.

has_obo_namespace

BrendaTissueOBO

has_related_synonym

alternatively activated macrophage

id

BTO:0006111

label

M2 macrophage

notation

BTO:0006111

prefLabel

M2 macrophage

treeView

http://purl.obolibrary.org/obo/BTO_0000801

subClassOf

http://purl.obolibrary.org/obo/BTO_0000801

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http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C123783 National Cancer Institute Thesaurus / 美国国家癌症研究所词典 LOOM