Human Phenotype Ontology / 人类表型本体

Last uploaded: September 7, 2023
Preferred Name

Granulomatosis

Definitions

This finding can be demonstrated by tissue biopsy. A granuloma is a compact (organized) collection of mature mononuclear phagocytes (macrophages and/or epithelioid cells) which may or may not be accompanied by accessory features such as necrosis or the infiltration of other inflammatory leukocytes (Adams DO. The granulomatous inflammatory response. Am J Pathol 1976:84:163-192). A granulomatous inflammation leading to multiple granuloma formation, which is a specific type of inflammation. A granuloma is a focal compact collection of inflammatory cells, mononuclear cells predominating, usually as a result of the persistence of a non-degradable product and of active cell mediated hypersensitivity.

ID

http://purl.obolibrary.org/obo/HP_0002955

comment

This finding can be demonstrated by tissue biopsy. A granuloma is a compact (organized) collection of mature mononuclear phagocytes (macrophages and/or epithelioid cells) which may or may not be accompanied by accessory features such as necrosis or the infiltration of other inflammatory leukocytes (Adams DO. The granulomatous inflammatory response. Am J Pathol 1976:84:163-192).

database_cross_reference

SNOMEDCT_US:44328006

SNOMEDCT_US:443138004

UMLS:C0521173

definition

A granulomatous inflammation leading to multiple granuloma formation, which is a specific type of inflammation. A granuloma is a focal compact collection of inflammatory cells, mononuclear cells predominating, usually as a result of the persistence of a non-degradable product and of active cell mediated hypersensitivity.

has_obo_namespace

human_phenotype

id

HP:0002955

label

Granulomatosis

notation

HP:0002955

prefLabel

Granulomatosis

treeView

http://purl.obolibrary.org/obo/HP_0004311

subClassOf

http://purl.obolibrary.org/obo/HP_0004311

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http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C113754 National Cancer Institute Thesaurus / 美国国家癌症研究所词典 LOOM