Human Phenotype Ontology / 人类表型本体

Last uploaded: September 7, 2023
Preferred Name

Mitochondrial swelling

Definitions

The mitochondrial matrix refers to the substance occupying the space enclosed by the inner membrane of a mitochondrion, which contains enzymes, DNA, granules, and inclusions of protein crystals, glycogen, and lipid. Mitochondrial swelling refers to an increase in size of the mitochondrial matrix. This phenomenon is thought to be related to a permeabilized inner membrane that originates a large swelling in the mitochondrial matrix. Mitochondrial swelling may distend the outer membrane until it ruptures.

ID

http://purl.obolibrary.org/obo/HP_0030774

database_cross_reference

SNOMEDCT_US:125429001

UMLS:C0026244

MSH:D008933

definition

The mitochondrial matrix refers to the substance occupying the space enclosed by the inner membrane of a mitochondrion, which contains enzymes, DNA, granules, and inclusions of protein crystals, glycogen, and lipid. Mitochondrial swelling refers to an increase in size of the mitochondrial matrix. This phenomenon is thought to be related to a permeabilized inner membrane that originates a large swelling in the mitochondrial matrix. Mitochondrial swelling may distend the outer membrane until it ruptures.

has_obo_namespace

human_phenotype

id

HP:0030774

label

Mitochondrial swelling

notation

HP:0030774

prefLabel

Mitochondrial swelling

treeView

http://purl.obolibrary.org/obo/HP_0012087

subClassOf

http://purl.obolibrary.org/obo/HP_0012087

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http://purl.bioontology.org/ontology/MESH/D008933 Medical Subject Headings / 医学主题词表 LOOM