Human Phenotype Ontology / 人类表型本体

Last uploaded: September 7, 2023
Preferred Name

Rosette

Definitions

Rosettes are named for the flower-like architectural ornament, this pattern resembles the rose windows found in many gothic cathedrals. Rosettes may be considered primary or secondary manifestations of tumor architecture. Primary rosettes form as a characteristic growth pattern of a given tumor type, whereas secondary rosettes result from the influence of external factors on tumor growth. A halo or spoke-wheel arrangement of cells surrounding a central core or hub. The central hub may consist of an empty-appearing lumen or a space filled with cytoplasmic processes. The cytoplasm of each of the cells in the rosette is often wedge-shaped with the apex directed toward the central core; the nuclei of the cells participating in the rosette are peripherally positioned and form a ring or halo around the hub.

ID

http://purl.obolibrary.org/obo/HP_0031925

comment

Rosettes are named for the flower-like architectural ornament, this pattern resembles the rose windows found in many gothic cathedrals. Rosettes may be considered primary or secondary manifestations of tumor architecture. Primary rosettes form as a characteristic growth pattern of a given tumor type, whereas secondary rosettes result from the influence of external factors on tumor growth.

creator

https://orcid.org/0000-0002-0736-9199

date

2018-07-04T13:22:47Z

definition

A halo or spoke-wheel arrangement of cells surrounding a central core or hub. The central hub may consist of an empty-appearing lumen or a space filled with cytoplasmic processes. The cytoplasm of each of the cells in the rosette is often wedge-shaped with the apex directed toward the central core; the nuclei of the cells participating in the rosette are peripherally positioned and form a ring or halo around the hub.

has_obo_namespace

human_phenotype

id

HP:0031925

label

Rosette

notation

HP:0031925

prefLabel

Rosette

treeView

http://purl.obolibrary.org/obo/HP_0025461

subClassOf

http://purl.obolibrary.org/obo/HP_0025461

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