Preferred Name |
Focal active colitis |
Definitions |
Focal active colitis (FAC) is characterized by focal crypt damage caused by neutrophils. FAC is characterized by an inflammatory infiltrate consisting of intraepithelial neutrophils and/or neutrophils invading the lumen of the criptae, with no other microscopic alteration of the colonic mucosa and, in particular, without the presence of signs of chronic inflammation. Focal crypt injury by neutrophils (cryptitis/crypt abscesses), or focal active colitis (FAC), is a common isolated finding in endoscopic colorectal biopsies. Focal active colitis is often thought of as a feature of Crohn's disease, but may also be seen in ischemia, infections, partially treated ulcerative colitis, and as an isolated finding in patients undergoing endoscopy to exclude neoplasia. |
ID |
http://purl.obolibrary.org/obo/HP_0033164 |
comment |
Focal crypt injury by neutrophils (cryptitis/crypt abscesses), or focal active colitis (FAC), is a common isolated finding in endoscopic colorectal biopsies. Focal active colitis is often thought of as a feature of Crohn's disease, but may also be seen in ischemia, infections, partially treated ulcerative colitis, and as an isolated finding in patients undergoing endoscopy to exclude neoplasia. |
creator | |
date |
2020-09-24T09:27:12Z |
definition |
Focal active colitis (FAC) is characterized by focal crypt damage caused by neutrophils. FAC is characterized by an inflammatory infiltrate consisting of intraepithelial neutrophils and/or neutrophils invading the lumen of the criptae, with no other microscopic alteration of the colonic mucosa and, in particular, without the presence of signs of chronic inflammation. |
has_obo_namespace |
human_phenotype |
id |
HP:0033164 |
label |
Focal active colitis |
notation |
HP:0033164 |
prefLabel |
Focal active colitis |
treeView | |
subClassOf |
Delete | Mapping To | Ontology | Source |
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http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C27740 | National Cancer Institute Thesaurus / 美国国家癌症研究所词典 | LOOM |