loading...| Preferred Name |
Amino Acid Substitution |
| Synonyms |
Amino Acid Substitutions |
| Definitions |
The naturally occurring or experimentally induced replacement of one or more AMINO ACIDS in a protein with another. If a functionally equivalent amino acid is substituted, the protein may retain wild-type activity. Substitution may also diminish, enhance, or eliminate protein function. Experimentally induced substitution is often used to study enzyme activities and binding site properties. |
| ID |
http://purl.bioontology.org/ontology/MESH/D019943 |
| altLabel |
Amino Acid Substitutions Substitutions, Amino Acid Substitution, Amino Acid |
| AQL |
DE GE IM PH RE |
| cui |
C0525038 |
| DC |
1 |
| definition |
The naturally occurring or experimentally induced replacement of one or more AMINO ACIDS in a protein with another. If a functionally equivalent amino acid is substituted, the protein may retain wild-type activity. Substitution may also diminish, enhance, or eliminate protein function. Experimentally induced substitution is often used to study enzyme activities and binding site properties. |
| DX |
19980101 |
| FX |
D020125 D016297 |
| HN |
98 |
| Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000187 http://purl.bioontology.org/ontology/MESH/Q000528 http://purl.bioontology.org/ontology/MESH/Q000235 |
| Inverse of RO | |
| Machine permutation |
98 |
| MDA |
19970620 |
| MMR |
20160115 |
| MN |
G05.558.109 E05.393.420.601.035 |
| notation |
D019943 |
| prefLabel |
Amino Acid Substitution |
| TERMUI |
T059440 |
| TH |
NLM (1998) |
| tui |
T045 |
| subClassOf |
| Delete | Mapping To | Ontology | Source |
|---|---|---|---|
| http://purl.obolibrary.org/obo/SO_0001606 | Sequence Types and Features Ontology / 序列类型和特征本体 | LOOM | |
| http://purl.obolibrary.org/obo/SO_0001606 | Human Disease Ontology / 人类疾病本体 | LOOM |