loading...| Preferred Name |
Shelterin Complex |
| Synonyms |
Complex, POT1-TPP1 Shelterin |
| Definitions |
A TELOMERE cap complex consisting of telomere-specific proteins in association with telomeric DNA such as telomeric dsDNA-sDNA junction. They are involved in the protection of chromosome ends and TELOMERASE regulation and play a role in CELLULAR SENESCENCE and ageing-related pathology. In general it consists of six mostly TELOMERE-BINDING PROTEINS (POT1, RAP1, TIN2, TPP1, TRF1, and TRF2). |
| ID |
http://purl.bioontology.org/ontology/MESH/D000089804 |
| altLabel |
Complex, POT1-TPP1 Shelterin Telosomes Telomere POT1-TPP1 Complex Complex, Telomeric Capping Telomere Cap Complex Telomeric Capping Complex POT1-TPP1 Complex, Telomere Ctc1 Stn1 Ten1 Complex Capping Complex, Telomeric Complex, Shelterin Telomeric Stn1 Ten1 Capping Complex Telomere POT1 TPP1 Complex Complex, Telomere POT1-TPP1 POT1-TPP1 Shelterin Complex POT1 TPP1 Shelterin Complex Telomeric Stn1-Ten1 Capping Complex Complex, CST Shelterin Complex, POT1-TPP1 Complex, Ctc1-Stn1-Ten1 CST Complex Ctc1-Stn1-Ten1 Complex Telosome |
| AQL |
AD AE AG AI AN BI BL CF CH CL CS DE DF EC GE HI IM IP ME PD PH PK PO RE SD ST TO TU UL UR |
| cui |
C5445115 C5445116 C3889653 C5545244 |
| DC |
1 |
| definition |
A TELOMERE cap complex consisting of telomere-specific proteins in association with telomeric DNA such as telomeric dsDNA-sDNA junction. They are involved in the protection of chromosome ends and TELOMERASE regulation and play a role in CELLULAR SENESCENCE and ageing-related pathology. In general it consists of six mostly TELOMERE-BINDING PROTEINS (POT1, RAP1, TIN2, TPP1, TRF1, and TRF2). |
| DX |
20220101 |
| HN |
2022 |
| Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000819 http://purl.bioontology.org/ontology/MESH/Q000187 http://purl.bioontology.org/ontology/MESH/Q000096 http://purl.bioontology.org/ontology/MESH/Q000037 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000528 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000235 http://purl.bioontology.org/ontology/MESH/Q000648 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000652 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000502 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000600 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000172 |
| Inverse of RB |
0 |
| Machine permutation |
2022 |
| Mapped from |
http://purl.bioontology.org/ontology/MESH/C503876 http://purl.bioontology.org/ontology/MESH/C509571 http://purl.bioontology.org/ontology/MESH/C495876 http://purl.bioontology.org/ontology/MESH/C507326 http://purl.bioontology.org/ontology/MESH/C000607855 http://purl.bioontology.org/ontology/MESH/C059329 http://purl.bioontology.org/ontology/MESH/C560602 http://purl.bioontology.org/ontology/MESH/C440829 http://purl.bioontology.org/ontology/MESH/C548558 http://purl.bioontology.org/ontology/MESH/C474965 http://purl.bioontology.org/ontology/MESH/C440849 |
| MDA |
20210709 |
| MMR |
20210630 |
| MN |
G05.360.160.845.500 D12.776.260.735.625 A11.284.430.106.279.345.190.160.845.500 D12.776.664.981 D05.500.918 D12.776.660.235.700.625 |
| notation |
D000089804 |
| prefLabel |
Shelterin Complex |
| TERMUI |
T001102218 T001102215 T001102209 T001102213 T001102219 T001102216 T001102224 T001102220 T001102217 |
| TH |
NLM (2022) |
| tui |
T116 T123 |
| subClassOf |
http://purl.bioontology.org/ontology/MESH/D046912 http://purl.bioontology.org/ontology/MESH/D034501 |
| Delete | Mapping To | Ontology | Source |
|---|---|---|---|
| http://purl.obolibrary.org/obo/GO_0070187 | Gene Ontology / 基因本体 | LOOM | |
| http://purl.obolibrary.org/obo/GO_0070187 | Protein Ontology / 蛋白质本体 | LOOM |