Medical Subject Headings / 医学主题词表

Last uploaded: September 7, 2023
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Preferred Name

2-Isopropylmalate Synthase
Synonyms

Synthase, 2-Isopropylmalate
Definitions

An enzyme that catalyzes the first step in the biosynthetic pathway to LEUCINE, forming isopropyl malate from acetyl-CoA and alpha-ketoisovaleric acid. This enzyme was formerly listed as EC 4.1.3.12.
ID

http://purl.bioontology.org/ontology/MESH/D015079
altLabel

Synthase, 2-Isopropylmalate

2 Isopropylmalate Synthase

Synthase, alpha-Isopropylmalate

3-Carboxy-3-hydroxy-4-methylpentanoate 3-methyl-2-oxobutanoate-lyase (CoA-acetylating)

alpha Isopropylmalate Synthase

alpha-Isopropylmalate Synthase
AQL

AD AE AI AN BI BL CF CH CL CS DE DF EC GE HI IM IP ME PD PH PK PO RE SD ST TO TU UL UR
cui

C0000291
DC

1
definition

An enzyme that catalyzes the first step in the biosynthetic pathway to LEUCINE, forming isopropyl malate from acetyl-CoA and alpha-ketoisovaleric acid. This enzyme was formerly listed as EC 4.1.3.12.
DX

19910101
HN

91(75); was see under KETOACID-LYASES 1975-90
Inverse of AQ

http://purl.bioontology.org/ontology/MESH/Q000032

http://purl.bioontology.org/ontology/MESH/Q000138

http://purl.bioontology.org/ontology/MESH/Q000737

http://purl.bioontology.org/ontology/MESH/Q000493

http://purl.bioontology.org/ontology/MESH/Q000145

http://purl.bioontology.org/ontology/MESH/Q000506

http://purl.bioontology.org/ontology/MESH/Q000187

http://purl.bioontology.org/ontology/MESH/Q000096

http://purl.bioontology.org/ontology/MESH/Q000037

http://purl.bioontology.org/ontology/MESH/Q000134

http://purl.bioontology.org/ontology/MESH/Q000592

http://purl.bioontology.org/ontology/MESH/Q000528

http://purl.bioontology.org/ontology/MESH/Q000008

http://purl.bioontology.org/ontology/MESH/Q000235

http://purl.bioontology.org/ontology/MESH/Q000648

http://purl.bioontology.org/ontology/MESH/Q000276

http://purl.bioontology.org/ontology/MESH/Q000191

http://purl.bioontology.org/ontology/MESH/Q000633

http://purl.bioontology.org/ontology/MESH/Q000652

http://purl.bioontology.org/ontology/MESH/Q000009

http://purl.bioontology.org/ontology/MESH/Q000302

http://purl.bioontology.org/ontology/MESH/Q000502

http://purl.bioontology.org/ontology/MESH/Q000494

http://purl.bioontology.org/ontology/MESH/Q000266

http://purl.bioontology.org/ontology/MESH/Q000600

http://purl.bioontology.org/ontology/MESH/Q000378

http://purl.bioontology.org/ontology/MESH/Q000172

http://purl.bioontology.org/ontology/MESH/Q000097

http://purl.bioontology.org/ontology/MESH/Q000627
Inverse of RB

EC 2.3.3.13
Machine permutation

91; was see under KETOACID-LYASES 1975-90
Mapped from

http://purl.bioontology.org/ontology/MESH/C000605328

http://purl.bioontology.org/ontology/MESH/C521944

http://purl.bioontology.org/ontology/MESH/C080062
MDA

19741119
MMR

20050630
MN

D08.811.913.050.614
notation

D015079
prefLabel

2-Isopropylmalate Synthase
RR

9030-98-2 (CAS RN)
TERMUI

T043990

T043989
TH

NLM (1975)

UNK (19XX)
tui

T116

T126
subClassOf

http://purl.bioontology.org/ontology/MESH/D000217
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http://purl.obolibrary.org/obo/PR_000023081 Protein Ontology / 蛋白质本体 LOOM