loading...| Preferred Name |
Endothelial PAS Domain-Containing Protein 1 |
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C104306 |
| code |
C104306 |
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977 |
| Contributing_Source |
CTRP |
| DEFINITION |
Endothelial PAS domain-containing protein 1 (870 aa, ~96 kDa) is encoded by the human EPAS1 gene. This protein plays a role in both the response to hypoxia and transcriptional regulation. |
| DesignNote |
Endothelial PAS domain-containing protein 1 binds to the DNA sequence 5'-[AG]CGTG-3' found within the hypoxia response element (HRE). (UniProt) |
| Display_Name |
Endothelial PAS Domain-Containing Protein 1 |
| FULL_SYN |
PAS Domain-Containing Protein 2 EPAS1 Hypoxia-Inducible Factor 2-Alpha HIF-1 Alpha-Like Factor Class E Basic Helix-Loop-Helix Protein 73 Endothelial PAS Domain-Containing Protein 1 Hypoxia-Inducible Factor 2 Alpha HIF-1-Alpha-Like Factor HLF Basic-Helix-Loop-Helix-PAS Protein MOP2 bHLHe73 HIF-1alpha-Like Factor Member of PAS Protein 2 EPAS-1 HIF2-Alpha HIF-2-Alpha |
| label |
Endothelial PAS Domain-Containing Protein 1 |
| OMIM_Number |
603349 |
| Preferred_Name |
Endothelial PAS Domain-Containing Protein 1 |
| prefixIRI |
Thesaurus:C104306 |
| prefLabel |
Endothelial PAS Domain-Containing Protein 1 |
| Semantic_Type |
Amino Acid, Peptide, or Protein |
| Swiss_Prot |
Q99814 |
| UMLS_CUI |
C1436532 |
| subClassOf |
| Delete | Mapping To | Ontology | Source |
|---|---|---|---|
| http://purl.bioontology.org/ontology/MESH/C105713 | Medical Subject Headings / 医学主题词表 | LOOM | |
| http://purl.obolibrary.org/obo/PR_000007106 | Protein Ontology / 蛋白质本体 | LOOM |