loading...| Preferred Name |
E3 Ubiquitin-Protein Ligase RING2 |
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C150306 |
| code |
C150306 |
| DEFINITION |
E3 ubiquitin-protein ligase RING2 (336 aa, ~38 kDa) is encoded by the human RNF2 gene. This protein is involved in both transcriptional repression and the monoubiquitination of lysine-119 of histone H2A. |
| DesignNote |
E3 ubiquitin-protein ligase RING2 is a member of a Polycomb group (PcG) protein complex that plays a role in transcriptional repression of genes during embryonic development and in imprinting. |
| FULL_SYN |
HIP2-Interacting Protein 3 RING Finger Protein 1B RNF2 Protein DinG E3 Ubiquitin-Protein Ligase RING2 RING Finger Protein BAP-1 RING-Type E3 Ubiquitin Transferase RING2 Huntingtin-Interacting Protein 2-Interacting Protein 3 RING Finger Protein 2 EC 2.3.2.27 RING1b |
| label |
E3 Ubiquitin-Protein Ligase RING2 |
| OMIM_Number |
608985 |
| Preferred_Name |
E3 Ubiquitin-Protein Ligase RING2 |
| prefixIRI |
Thesaurus:C150306 |
| prefLabel |
E3 Ubiquitin-Protein Ligase RING2 |
| Semantic_Type |
Enzyme |
| Swiss_Prot |
Q99496 |
| UMLS_CUI |
C1455461 |
| subClassOf |
| Delete | Mapping To | Ontology | Source |
|---|---|---|---|
| http://purl.obolibrary.org/obo/PR_000014115 | Protein Ontology / 蛋白质本体 | LOOM |