loading...| Preferred Name |
Serpin B5 |
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17790 |
| code |
C17790 |
| DEFINITION |
Serpin B5 (375 aa, ~42 kDa) is encoded by the human SERPINB5 gene. This protein plays a role in the regulation of cell movement and in tumor suppression. |
| DesignNote |
Maspin is a member of the Serpin protein family. Unlike other members of the family, Maspin exhibits no protease inhibitory activity (see J Biol Chem. 2002 Dec 6;277(49):46845-8. Epub 2002 Oct 15), but it plays a role in cell-matrix adhesion, tumor invasion, and metastasis. High maspin expression appears to oppose lymph node metastasis. Higher expression is associated with better survival rates and may be a favorable prognostic marker. (from SWISS-PROT, OMIM) |
| FULL_SYN |
Maspin Protease Inhibitor 5 PI-5 Serpin B5 SERPINB5 PI5 |
| label |
Serpin B5 |
| Legacy Concept Name |
Maspin |
| OMIM_Number |
154790 |
| Preferred_Name |
Serpin B5 |
| prefixIRI |
Thesaurus:C17790 |
| prefLabel |
Serpin B5 |
| Semantic_Type |
Amino Acid, Peptide, or Protein |
| Swiss_Prot |
P36952 |
| UMLS_CUI |
C1568102 |
| subClassOf |