Preferred Name

Insulin Signaling Pathway

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C39130

ALT_DEFINITION

The appropriate signaling through the insulin pathway is critical for the regulation of glucose levels and the avoidance of diabetes. Insulin forms a complex with the insulin receptor (IR) and b chains to form the active signaling complex. Through recruitment of adaptor molecules and the activation of RAS, the activated IR can cause transcriptional activation. (This definition may be outdated - see the DesignNote.)

BioCarta_ID

h_insulinPathway

code

C39130

DesignNote

The BIOCARTA Definition (ALT_DEFINITION) for this pathway concept was provided by BioCarta. This property was not created by, nor is it maintained by the NCI Thesaurus staff. Additionally, BioCarta is no longer updating its pathway data; thus, the BIOCARTA Definition might be outdated or inaccurate. Please see the Terms and Conditions for Use at http://www.biocarta.com/.

FULL_SYN

Insulin Signaling Pathway

label

Insulin Signaling Pathway

Legacy Concept Name

Insulin_Signaling_Pathway

Preferred_Name

Insulin Signaling Pathway

prefixIRI

Thesaurus:C39130

prefLabel

Insulin Signaling Pathway

Semantic_Type

Functional Concept

UMLS_CUI

C1512804

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17132

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http://purl.obolibrary.org/obo/PW_0000143 Pathway Ontology / 通路本体 LOOM