| Preferred Name |
Histone Deacetylation |
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C40580 |
| code |
C40580 |
| DEFINITION |
Histone Deacetylation is the covalent post-translational enzymatic removal of acetyl group(s) from a histone protein. By exposing cationic sites on the protein that promote ionic interaction with the negatively charged DNA backbone, Histone Deacetylation induces DNA condensation and regulates genetic functions, such as transcription. (NCI) |
| FULL_SYN |
Histone Deacetylation |
| label |
Histone Deacetylation |
| Legacy Concept Name |
Histone_Deacetylation |
| Preferred_Name |
Histone Deacetylation |
| prefixIRI |
Thesaurus:C40580 |
| prefLabel |
Histone Deacetylation |
| Semantic_Type |
Physiologic Function |
| UMLS_CUI |
C1156201 |
| subClassOf |
| Delete | Mapping To | Ontology | Source |
|---|---|---|---|
| http://purl.obolibrary.org/obo/GO_0016575 | Gene Ontology / 基因本体 | LOOM |