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loading...| Preferred Name |
Pumitepa |
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C73239 |
| CAS_Registry |
42061-52-9 |
| Chemical_Formula |
C12H19N8OP |
| code |
C73239 |
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157712 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C177537 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157711 |
| Contributing_Source |
GDC FDA |
| DEFINITION |
A thiotepa derivative with potential antineoplastic alkylating activity. Although the exact mechanism of action of pumitepa has yet to be fully elucidated, this agent appears to work through alkylation, thereby causing DNA damage and cell cycle arrest. |
| FDA_UNII_Code |
7AYY495RE0 |
| FULL_SYN |
Fopurin Pumitepa PUMITEPA |
| Is_Value_For_GDC_Property | |
| label |
Pumitepa |
| Legacy Concept Name |
Pumitepa |
| Maps_To |
Pumitepa |
| Preferred_Name |
Pumitepa |
| prefixIRI |
Thesaurus:C73239 |
| prefLabel |
Pumitepa |
| Semantic_Type |
Pharmacologic Substance |
| UMLS_CUI |
C0060632 |
| subClassOf |
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| Delete | Mapping To | Ontology | Source |
|---|---|---|---|
| http://purl.bioontology.org/ontology/MESH/C015893 | Medical Subject Headings / 医学主题词表 | LOOM |