loading...| Preferred Name |
insulin signaling pathway |
| Synonyms |
Signaling by Insulin receptor insulin receptor signaling pathway |
| Definitions |
Insulin, the peptide hormone secreted by pancreatic beta cells, plays essential roles in glucose and energy homeostasis. Insulin signaling activates two main intracellular pathways to regulate carbohydrate and fat metabolism and to prompt glucose absorption in insulin sensitive tissues such as skeletal muscle and adipocytes. Deregulation of the pathway has been associated with a number of conditions, primarily diabetes. |
| ID |
http://purl.obolibrary.org/obo/PW_0000143 |
| definition |
Insulin, the peptide hormone secreted by pancreatic beta cells, plays essential roles in glucose and energy homeostasis. Insulin signaling activates two main intracellular pathways to regulate carbohydrate and fat metabolism and to prompt glucose absorption in insulin sensitive tissues such as skeletal muscle and adipocytes. Deregulation of the pathway has been associated with a number of conditions, primarily diabetes. |
| has_obo_namespace |
pathway |
| has_related_synonym |
Signaling by Insulin receptor insulin receptor signaling pathway |
| id |
PW:0000143 |
| label |
insulin signaling pathway |
| notation |
PW:0000143 |
| part_of | |
| prefLabel |
insulin signaling pathway |
| treeView |
http://purl.obolibrary.org/obo/PW_0000357 |
| subClassOf |
| Delete | Mapping To | Ontology | Source |
|---|---|---|---|
| http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C39130 | National Cancer Institute Thesaurus / 美国国家癌症研究所词典 | LOOM |