loading...| Preferred Name |
Hippo signaling pathway |
| Synonyms |
Signaling by Hippo hippo signaling |
| Definitions |
The Hippo signaling pathway plays important roles in organ development and growth and tumor suppression. The pathway consists of a core of four kinases which once activated by upstream regulators promote the cytoplasmic sequestration of YAP/TAZ transcriptional regulators. Dysregulation of the pathway has been implicated in tumor metastasis. |
| ID |
http://purl.obolibrary.org/obo/PW_0001515 |
| created_by |
VPetri |
| creation_date |
2014-03-19T11:27:29Z |
| definition |
The Hippo signaling pathway plays important roles in organ development and growth and tumor suppression. The pathway consists of a core of four kinases which once activated by upstream regulators promote the cytoplasmic sequestration of YAP/TAZ transcriptional regulators. Dysregulation of the pathway has been implicated in tumor metastasis. |
| has_obo_namespace |
pathway |
| has_related_synonym |
Signaling by Hippo hippo signaling |
| id |
PW:0001515 |
| label |
Hippo signaling pathway |
| notation |
PW:0001515 |
| prefLabel |
Hippo signaling pathway |
| treeView | |
| subClassOf |
| Delete | Mapping To | Ontology | Source |
|---|---|---|---|
| http://purl.bioontology.org/ontology/MESH/D000090683 | Medical Subject Headings / 医学主题词表 | LOOM |