loading...| Preferred Name |
tRNA |
| Synonyms |
transfer RNA INSDC_qualifier:unknown INSDC_feature:tRNA transfer ribonucleic acid |
| Definitions |
This term is mapped to MGED. Do not obsolete without consulting MGED ontology. Transfer RNA (tRNA) molecules are approximately 80 nucleotides in length. Their secondary structure includes four short double-helical elements and three loops (D, anti-codon, and T loops). Further hydrogen bonds mediate the characteristic L-shaped molecular structure. Transfer RNAs have two regions of fundamental functional importance: the anti-codon, which is responsible for specific mRNA codon recognition, and the 3' end, to which the tRNA's corresponding amino acid is attached (by aminoacyl-tRNA synthetases). Transfer RNAs cope with the degeneracy of the genetic code in two manners: having more than one tRNA (with a specific anti-codon) for a particular amino acid; and 'wobble' base-pairing, i.e. permitting non-standard base-pairing at the 3rd anti-codon position. |
| ID |
http://purl.obolibrary.org/obo/SO_0000253 |
| comment |
This term is mapped to MGED. Do not obsolete without consulting MGED ontology. |
| database_cross_reference | |
| definition |
Transfer RNA (tRNA) molecules are approximately 80 nucleotides in length. Their secondary structure includes four short double-helical elements and three loops (D, anti-codon, and T loops). Further hydrogen bonds mediate the characteristic L-shaped molecular structure. Transfer RNAs have two regions of fundamental functional importance: the anti-codon, which is responsible for specific mRNA codon recognition, and the 3' end, to which the tRNA's corresponding amino acid is attached (by aminoacyl-tRNA synthetases). Transfer RNAs cope with the degeneracy of the genetic code in two manners: having more than one tRNA (with a specific anti-codon) for a particular amino acid; and 'wobble' base-pairing, i.e. permitting non-standard base-pairing at the 3rd anti-codon position. |
| derives_from | |
| has_broad_synonym |
INSDC_qualifier:unknown |
| has_exact_synonym |
INSDC_feature:tRNA |
| has_obo_namespace |
sequence |
| has_related_synonym |
transfer RNA transfer ribonucleic acid |
| id |
SO:0000253 |
| in_subset | |
| label |
tRNA |
| notation |
SO:0000253 |
| prefLabel |
tRNA |
| subClassOf |