Cell Ontology / 细胞本体

Last uploaded: September 7, 2023
Preferred Name

pro-NK cell

Synonyms

NKP

natural killer cell progenitor

pro-natural killer cell

preNK cell

null cell

Definitions

A lymphoid progenitor cell that is committed to the natural killer cell lineage, expressing CD122 (IL-15) receptor, but lacking many of the phenotypic characteristics of later stages of natural killer cell development such as expression of NK activating and inhibitory molecules. In human this cell has the phenotype CD34-positive, CD45RA-positive, CD10-positive, CD117-negative, and CD161 negative. Most markers only described for human pro NK cells.

ID

http://purl.obolibrary.org/obo/CL_0000825

comment

Most markers only described for human pro NK cells.

definition

A lymphoid progenitor cell that is committed to the natural killer cell lineage, expressing CD122 (IL-15) receptor, but lacking many of the phenotypic characteristics of later stages of natural killer cell development such as expression of NK activating and inhibitory molecules. In human this cell has the phenotype CD34-positive, CD45RA-positive, CD10-positive, CD117-negative, and CD161 negative.

develops_from

http://purl.obolibrary.org/obo/CL_0000051

has plasma membrane part

http://purl.obolibrary.org/obo/PR_000001898

http://purl.obolibrary.org/obo/PR_000001003

http://purl.obolibrary.org/obo/PR_000001015

http://purl.obolibrary.org/obo/PR_000001381

has_exact_synonym

NKP

natural killer cell progenitor

pro-natural killer cell

has_related_synonym

preNK cell

null cell

label

pro-NK cell

lacks_plasma_membrane_part

http://purl.obolibrary.org/obo/PR_000002065

http://purl.obolibrary.org/obo/PR_000001874

prefixIRI

CL:0000825

prefLabel

pro-NK cell

treeView

http://purl.obolibrary.org/obo/CL_0000051

subClassOf

http://purl.obolibrary.org/obo/CL_0000838

http://purl.obolibrary.org/obo/PR_000050567

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http://purl.obolibrary.org/obo/CL_0000825 中国人类表型本体 / Human Phenotype Ontology China LOOM
http://purl.obolibrary.org/obo/CL_0000825 中国人类表型本体 / Human Phenotype Ontology China SAME_URI
http://purl.obolibrary.org/obo/CL_0000825 Experimental Factor Ontology / 实验性因素本体 LOOM
http://purl.obolibrary.org/obo/CL_0000825 Experimental Factor Ontology / 实验性因素本体 SAME_URI