loading...| Preferred Name |
Oropharyngeal Squamous Cell Carcinoma |
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C8181 |
| code |
C8181 |
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C126659 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C118168 |
| Contributing_Source |
CTRP Cellosaurus |
| DEFINITION |
A squamous cell carcinoma arising from the oropharynx. It predominantly affects adults in their fifth and sixth decades of life and is associated with alcohol and tobacco use. Human papillomavirus is present in approximately half of the cases. It is characterized by a tendency to metastasize early to the lymph nodes. When the tumor is small, patients are often asymptomatic. Physical examination may reveal erythematous or white lesions or plaques. The majority of patients present with locally advanced disease. Signs and symptoms include mucosal ulceration, pain, bleeding, weight loss, neck swelling, and difficulty speaking, chewing, and swallowing. Patients may also present with swollen neck lymph nodes without any symptoms from the oropharyngeal tumor. The most significant prognostic factors are the size of the tumor and the lymph nodes status. |
| Display_Name |
Oropharyngeal Squamous Cell Carcinoma |
| FULL_SYN |
Oropharyngeal Squamous Cell Carcinoma Oropharyngeal Throat Squamous Cell Cancer Epidermoid Carcinoma of the Oropharynx Epidermoid Carcinoma of Oropharynx Oropharyngeal Epidermoid Carcinoma Squamous Cell Carcinoma of the Oropharynx Squamous Cell Carcinoma of Oropharynx |
| label |
Oropharyngeal Squamous Cell Carcinoma |
| Legacy Concept Name |
Oropharyngeal_Squamous_Cell_Carcinoma |
| NCI_META_CUI |
CL497390 |
| Neoplastic_Status |
Malignant |
| Preferred_Name |
Oropharyngeal Squamous Cell Carcinoma |
| prefixIRI |
Thesaurus:C8181 |
| prefLabel |
Oropharyngeal Squamous Cell Carcinoma |
| Semantic_Type |
Neoplastic Process |
| subClassOf |