loading...| Preferred Name |
Prion Diseases |
| Synonyms |
Transmissible Spongiform Encephalopathy |
| Definitions |
A group of genetic, infectious, or sporadic degenerative human and animal nervous system disorders associated with abnormal PRIONS. These diseases are characterized by conversion of the normal prion protein to an abnormal configuration via a post-translational process. In humans, these conditions generally feature DEMENTIA; ATAXIA; and a fatal outcome. Pathologic features include a spongiform encephalopathy without evidence of inflammation. The older literature occasionally refers to these as unconventional SLOW VIRUS DISEASES. (From Proc Natl Acad Sci USA 1998 Nov 10;95(23):13363-83) |
| ID |
http://purl.bioontology.org/ontology/MESH/D017096 |
| altLabel |
Transmissible Spongiform Encephalopathy Prion Disease Encephalopathies, Spongiform, Transmissible Prion-Associated Disorders Spongiform Encephalopathies, Transmissible Dementias, Transmissible Disorder, Prion-Induced Dementia, Transmissible Prion Induced Disorder Human Transmissible Spongiform Encephalopathies, Inherited Prion Protein Diseases Prion Protein Disease Transmissible Dementias Transmissible Spongiform Encephalopathies Prion-Induced Disorders Inherited Human Transmissible Spongiform Encephalopathies Prion-Induced Disorder Disorders, Prion-Induced Transmissible Dementia Spongiform Encephalopathy, Transmissible Encephalopathy, Transmissible Spongiform Encephalopathies, Transmissible Spongiform |
| AN |
general or unspecified; prefer specifics |
| AQL |
BL CF CI CL CN CO DG DH DI DT EC EH EM EN EP ET GE HI IM ME MI MO NU PA PC PP PS PX RH RT SU TH TM UR VE VI |
| cui |
C0162534 C0751645 |
| DC |
1 |
| definition |
A group of genetic, infectious, or sporadic degenerative human and animal nervous system disorders associated with abnormal PRIONS. These diseases are characterized by conversion of the normal prion protein to an abnormal configuration via a post-translational process. In humans, these conditions generally feature DEMENTIA; ATAXIA; and a fatal outcome. Pathologic features include a spongiform encephalopathy without evidence of inflammation. The older literature occasionally refers to these as unconventional SLOW VIRUS DISEASES. (From Proc Natl Acad Sci USA 1998 Nov 10;95(23):13363-83) |
| DX |
19930101 |
| HN |
1993 |
| Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000401 http://purl.bioontology.org/ontology/MESH/Q000150 http://purl.bioontology.org/ontology/MESH/Q000188 http://purl.bioontology.org/ontology/MESH/Q000517 http://purl.bioontology.org/ontology/MESH/Q000201 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000503 http://purl.bioontology.org/ontology/MESH/Q000453 http://purl.bioontology.org/ontology/MESH/Q000208 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000821 http://purl.bioontology.org/ontology/MESH/Q000382 http://purl.bioontology.org/ontology/MESH/Q000601 http://purl.bioontology.org/ontology/MESH/Q000235 http://purl.bioontology.org/ontology/MESH/Q000523 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000652 http://purl.bioontology.org/ontology/MESH/Q000662 http://purl.bioontology.org/ontology/MESH/Q000151 http://purl.bioontology.org/ontology/MESH/Q000628 http://purl.bioontology.org/ontology/MESH/Q000196 http://purl.bioontology.org/ontology/MESH/Q000534 http://purl.bioontology.org/ontology/MESH/Q000635 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000532 http://purl.bioontology.org/ontology/MESH/Q000139 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000175 http://purl.bioontology.org/ontology/MESH/Q000000981 http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000473 http://purl.bioontology.org/ontology/MESH/Q000451 http://purl.bioontology.org/ontology/MESH/Q000209 |
| Inverse of RO | |
| Machine permutation |
1993 |
| Mapped from | |
| MDA |
19920522 |
| MMR |
20190617 |
| MN |
C10.228.228.800 C10.574.843 C01.207.800 |
| notation |
D017096 |
| prefLabel |
Prion Diseases |
| TERMUI |
T051045 T051043 T370039 T842326 T842325 T370038 T370036 T051042 T370041 T051044 T842327 T370037 T370040 |
| TH |
NLM (1993) NLM (2000) GHR (2014) |
| tui |
T047 |
| subClassOf |