loading...| Preferred Name |
Bufogenin |
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C77829 |
| CAS_Registry |
465-39-4 |
| Chemical_Formula |
C24H32O4 |
| code |
C77829 |
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977 |
| Contributing_Source |
CTRP FDA |
| DEFINITION |
A bufadienolide toxin originally isolated from the venom of the Chinese toad Bufo gargarizans; it is also one of the glycosides in the traditional Chinese medicine ChanSu, with potential cardiotonic activity. Although the mechanism of action of bufogenin is still under investigation, this agent is a specific Na+/K+-ATPase inhibitor and has been shown to reduce blood pressure in a rat model of preeclampsia. |
| Display_Name |
Bufogenin |
| FDA_UNII_Code |
3K654P2M4J |
| FULL_SYN |
Resibufogenin BUFOGENIN Bufogenin 5beta-Bufa-20,22-Dienolide, 14,15beta-Epoxy-3beta-Hydroxy- (8CI) 14,15beta-Epoxy-3beta-Hydroxy-5beta-Bufa-20,22-Dienolide Respigon 14,15-Beta-Epoxy-3-Beta-Hydroxy-5-Beta-Bufa-20,22-Dienolide 3beta-Hydroxy-14,15beta-Epoxy-5beta-Bufa-20,22-Dienolide Bufa-20,22-Dienolide, 14,15-Epoxy-3-Hydroxy-, (3beta,5beta,15beta)- (9CI) 5-Beta-Bufa-20,22-Dienolide, 14,15-Beta-Epoxy-3-Beta-Hydroxy- 3-Beta-Hydroxy-14,15-Beta-Epoxy-5-Beta-Bufa-20,22-Dienolide |
| label |
Bufogenin |
| Legacy Concept Name |
Bufogenin |
| NSC Number |
90783 |
| Preferred_Name |
Bufogenin |
| prefixIRI |
Thesaurus:C77829 |
| prefLabel |
Bufogenin |
| Semantic_Type |
Pharmacologic Substance |
| UMLS_CUI |
C0054208 |
| subClassOf |