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loading...| Preferred Name |
Antithrombin-III |
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C104683 |
| code |
C104683 |
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977 |
| Contributing_Source |
CTRP |
| DEFINITION |
Antithrombin-III (464 aa, ~53 kDa) is encoded by the human SERPINC1 gene. This protein is involved in the negative regulation of serine proteinase activity during blood coagulation. |
| DesignNote |
Antithrombin-III can inhibit thrombin, matriptase-3/TMPRSS7, and coagulation factors IXa, Xa and Xia. (UniProt) |
| Display_Name |
Antithrombin-III |
| FULL_SYN |
Antithrombin III Serpin C1 Antithrombin-III SERPINC1 Serine-Cysteine Proteinase Inhibitor Clade C Member 1 ATIII |
| label |
Antithrombin-III |
| NCI_META_CUI |
CL360008 |
| OMIM_Number |
107300 |
| Preferred_Name |
Antithrombin-III |
| prefixIRI |
Thesaurus:C104683 |
| prefLabel |
Antithrombin-III |
| Semantic_Type |
Amino Acid, Peptide, or Protein |
| Swiss_Prot |
P01008 |
| subClassOf |
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