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loading...| Preferred Name |
Fluoroquinolone Antibiotic |
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C126712 |
| code |
C126712 |
| Concept_In_Subset | |
| Contributing_Source |
CTRP |
| DEFINITION |
Any quinolone antibiotic with a fluorine (F) atom attached to the quinolone structure, with broad-spectrum antibacterial activity. Fluoroquinolones diffuse through the bacterial cell wall and act by inhibiting bacterial topoisomerase II, DNA gyrase and/or bacterial topoisomerase IV, which are enzymes involved in bacterial DNA replication. This prevents DNA replication and leads to a blockage of bacterial cell proliferation. |
| Display_Name |
Fluoroquinolone Antibiotic |
| FULL_SYN |
Fluoroquinolone Fluoroquinolone Antibiotic Fluoroquinolones |
| label |
Fluoroquinolone Antibiotic |
| Preferred_Name |
Fluoroquinolone Antibiotic |
| prefixIRI |
Thesaurus:C126712 |
| prefLabel |
Fluoroquinolone Antibiotic |
| Semantic_Type |
Chemical Viewed Functionally |
| UMLS_CUI |
C0949665 |
| subClassOf |
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| Delete | Mapping To | Ontology | Source |
|---|---|---|---|
| http://purl.obolibrary.org/obo/CHEBI_87211 | Chemical Entities of Biological Interest Ontology / 生物相关的化学实体本体 | LOOM | |
| http://purl.obolibrary.org/obo/CHEBI_87211 | The Drug Ontology / 药物本体 | LOOM |