loading...| Preferred Name |
5-Methylcytosine |
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C129008 |
| CAS_Registry |
554-01-8 |
| CHEBI_ID |
CHEBI:27551 |
| code |
C129008 |
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977 |
| Contributing_Source |
CTRP FDA |
| DEFINITION |
A methylated form of the nucleobase cytosine occurring predominantly in cytosine-phosphate-guanine (CpG) islands that are produced by DNA methyltransferases and may regulate gene expression. Like cytosine, the DNA sequence containing 5-methylcytosine (5-mC) is able to be replicated without error and 5-mC can pair with guanine in double stranded DNA. However, DNA sequences containing a high local concentration of 5-mC may be less transcriptionally active than areas with higher ratios of unmodified cytosine. |
| Display_Name |
5-Methylcytosine |
| FDA_UNII_Code |
6R795CQT4H |
| FULL_SYN |
5-METHYLCYTOSINE 5-Methylcytosine |
| label |
5-Methylcytosine |
| Preferred_Name |
5-Methylcytosine |
| prefixIRI |
Thesaurus:C129008 |
| prefLabel |
5-Methylcytosine |
| Semantic_Type |
Nucleic Acid, Nucleoside, or Nucleotide |
| UMLS_CUI |
C0049308 |
| subClassOf |