loading...| Preferred Name |
Fibronectin |
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C16581 |
| code |
C16581 |
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977 |
| Contributing_Source |
CTRP |
| DEFINITION |
Fibronectin (2386 aa, ~263 kDa) is encoded by the human FN1 gene. This protein is involved in cell adhesion- and migration-dependent processes including embryogenesis, wound healing, blood coagulation, host defense, and metastasis. |
| DesignNote |
Fibronectin can be cleaved to form Ugl-Y1, Ugl-Y2, Ugl-Y3 and anastellin. (UniProt) Anastellin is a 76 amino acid fragment from carboxy-terminal portion of the first fibronectin type-III domain with potential antiangiogenic activity. Anastellin binds fibronectin and induces fibril formation; the resulting fibronectin polymer, superfibronectin, exhibits enhanced adhesive properties and may also inhibit angiogenesis. (UniProt) |
| Display_Name |
Fibronectin |
| FULL_SYN |
FN1 Large, External, Transformation-Sensitive Protein Fibronectin FNZ Large External Transformation-Sensitive Protein CIG Cold-Insoluble Globulin LETS Protein LETS FN Fibronectin 1 |
| label |
Fibronectin |
| Legacy Concept Name |
Fibronectin |
| NCI_META_CUI |
CL1379609 |
| OMIM_Number |
135600 |
| Preferred_Name |
Fibronectin |
| prefixIRI |
Thesaurus:C16581 |
| prefLabel |
Fibronectin |
| Semantic_Type |
Amino Acid, Peptide, or Protein |
| Swiss_Prot |
P02751 |
| subClassOf |