Preferred Name

Aptamer

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1749

code

C1749

DEFINITION

Double-stranded DNA or single-stranded RNA oligonucleotide sequences with the capacity to recognize target molecules with high affinity and specificity. Fundamentally distinct from antibodies, aptamers mimic their properties and have emerged as a promising class of molecules in both therapeutic and diagnostic formats. In having small size (8-15 kDa) relative to antibodies (150 kDa), aptamers are candidates for rapid tumor penetration and blood clearance.

FULL_SYN

Aptamer

label

Aptamer

Legacy Concept Name

Aptamer

Preferred_Name

Aptamer

prefixIRI

Thesaurus:C1749

prefLabel

Aptamer

Semantic_Type

Nucleic Acid, Nucleoside, or Nucleotide

UMLS_CUI

C0599013

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C706

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http://purl.obolibrary.org/obo/SO_0000031 Sequence Types and Features Ontology / 序列类型和特征本体 LOOM
http://purl.obolibrary.org/obo/CHEBI_140488 Chemical Entities of Biological Interest Ontology / 生物相关的化学实体本体 LOOM