loading...| Preferred Name |
Cyclin-Dependent Kinase 5 |
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17785 |
| code |
C17785 |
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977 |
| Contributing_Source |
CTRP |
| DEFINITION |
Cyclin-dependent kinase 5 (292 aa, ~33 kDa) is encoded by the human CDK5 gene. This protein plays a role in protein phosphorylation and may be involved in cell cycle regulation. |
| DesignNote |
A hetero-dimeric (catalytic/regulatory subunits) serine/threonine protein kinase involved in cell cycle control. Predominantly neuronal, Cdk5 belongs to the CDC2/CDKX subfamily, interacts with D1- and D3-type G1 Cyclins, and phosphorylates histone H1, Tau, Map2, NF-H, and NF-M. (from SWISS-PROT, OMIM) |
| Display_Name |
Cyclin-Dependent Kinase 5 |
| FULL_SYN |
Cell Division Kinase 5 Serine/Threonine-Protein Kinase PSSALRE EC 2.7.11.22 Cell Division Protein Kinase 5 TPKII Catalytic Subunit Cyclin-Dependent Kinase 5 Tau Protein Kinase II Catalytic Subunit Cyclin-Dependent Kinase-5 CDK5 |
| label |
Cyclin-Dependent Kinase 5 |
| Legacy Concept Name |
Cyclin-Dependent_Kinase-5 |
| OMIM_Number |
123831 |
| Preferred_Name |
Cyclin-Dependent Kinase 5 |
| prefixIRI |
Thesaurus:C17785 |
| prefLabel |
Cyclin-Dependent Kinase 5 |
| Semantic_Type |
Enzyme Amino Acid, Peptide, or Protein |
| Swiss_Prot |
Q00535 |
| UMLS_CUI |
C1565306 |
| subClassOf |