loading...| Preferred Name |
Quinupristin |
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47701 |
| CAS_Registry |
120138-50-3 |
| Chemical_Formula |
C53H67N9O10S |
| code |
C47701 |
| Concept_In_Subset | |
| Contributing_Source |
FDA |
| DEFINITION |
A semi-synthetic derivative of pristinamycin, a natural occurring type B streptogramin. Quinupristin binds to the bacterial 50S ribosomal subunit, thereby inhibiting peptide chain elongation, and causing early termination of normal bacterial protein synthesis. Quinupristin is primarily effective against gram-positive cocci. |
| FDA_UNII_Code |
23OW28RS7P |
| FULL_SYN |
N-((6R,9S,10R,13S,15aS,18R,22S,24aS)-22-(p-(Dimethylamino)benzyl)-6-ethyldocosahydro-10,23-dimethyl-5,8,12,15,17,21,24-heptaoxo-13-phenyl-18-(((3S)-3-quinuclidinylthio)methyl)-12H-pyrido(2,1-f)pyrrolo(2,1-l)(1,4,7,10,13,16)oxapentaazacyclononadecin-9-yl)-3-hydroxypicolinamide Virginiamycin S1, 4-(4-(dimethylamino)-N-methyl-L-phenylalanine)-5-(5-((1-azabicyclo(2.2.2)oct-3-ylthio)methyl)-4-oxo-L-2-piperidinecarboxylic Acid)-,(S)- Quinupristin QUINUPRISTIN |
| label |
Quinupristin |
| Legacy Concept Name |
Quinupristin |
| Preferred_Name |
Quinupristin |
| prefixIRI |
Thesaurus:C47701 |
| prefLabel |
Quinupristin |
| Semantic_Type |
Pharmacologic Substance |
| UMLS_CUI |
C0756081 |
| subClassOf |