loading...| Preferred Name |
Clusterin |
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C84432 |
| code |
C84432 |
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977 |
| Contributing_Source |
CTRP |
| DEFINITION |
Clusterin (449 aa, ~52 kDa) is encoded by the human CLU gene. This protein may be involved in lipid metabolism, complement regulation and the initiation of apoptosis. |
| DesignNote |
Clusterin can be cleaved into alpha and beta chains that are also known as ApoJ alpha and ApoJ beta. The two chains form an antiparallel disulfide-linked heterodimer. (UniProt) |
| Display_Name |
Clusterin |
| FULL_SYN |
CLI Apolipoprotein J Complement-Associated Protein SP-40,40 Clusterin Complement Lysis Inhibitor Aging-Associated Gene 4 Protein Apo-J Ku70-Binding Protein 1 Complement Cytolysis Inhibitor NA1/NA2 TRPM-2 Sulfated Glycoprotein 2 Testosterone-Repressed Prostate Message 2 |
| label |
Clusterin |
| OMIM_Number |
185430 |
| Preferred_Name |
Clusterin |
| prefixIRI |
Thesaurus:C84432 |
| prefLabel |
Clusterin |
| Semantic_Type |
Amino Acid, Peptide, or Protein |
| Swiss_Prot |
P10909 |
| UMLS_CUI |
C0055966 |
| subClassOf |