loading...| Preferred Name |
Hyperkeratosis lenticularis perstans |
| ID |
http://www.orpha.net/ORDO/Orphanet_409 |
| alternative_term |
Flegel disease |
| definition |
A rare skin disease characterized by usually asymptomatic, hyperkeratotic, reddish-brown papules primarily located on the lower extremities. Histological examination shows lamellar hyperkeratosis with abrupt peripheral basket-weave orthokeratosis, irregular acanthosis, and underlying lichenoid lymphocytic infiltrate. The condition may be sporadic or familial. |
| definition_citation |
Orphanet |
| expertlink |
https://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=409 |
| has_age_of_onset |
Adult |
| has_inheritance |
Not applicable Autosomal dominant |
| hasDbXref |
ICD-10:L98.8 MeSH:C538377 MedDRA:10071311 ICD-11:ED5Y OMIM:144150 UMLS:C0263420 |
| label |
Hyperkeratosis lenticularis perstans |
| notation |
ORPHA:409 |
| part_of | |
| prefixIRI |
ORDO:Orphanet_409 |
| prefLabel |
Hyperkeratosis lenticularis perstans |
| present_in |
Worldwide AND has_point_prevalence_range : Unknown |
| treeView | |
| subClassOf |