loading...| Preferred Name |
Interleukin-4 |
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C20508 |
| ALT_DEFINITION |
One of a group of related proteins made by leukocytes (white blood cells) and other cells in the body. Interleukin-4 is made by a type of T lymphocyte. It causes B lymphocytes to increase and to make antibodies and also increases the production of T lymphocytes. Interleukin-4 made in the laboratory is used as a biological response modifier to boost the immune system in cancer therapy. Interleukin-4 is a type of cytokine. |
| code |
C20508 |
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977 |
| Contributing_Source |
CTRP |
| DEFINITION |
Interleukin-4 (153 aa, ~17 kDa) is encoded by the human IL4 gene. This protein is involved in the regulation of the expression of class II MHC molecules, Fc receptors and cell surface-bound immunoglobulins. |
| Display_Name |
Interleukin-4 |
| FULL_SYN |
IL4 BCDF-1 Lymphocyte Stimulatory Factor 1 IL4 Protein B Cell Proliferating Factor BCGF-1 B-Cell Growth Factor BSF1 BSF-1 B-Cell Growth Factor-1 BCGF B-Cell Differentiation Factor-1 Interleukin 4 Mast Cell Growth Factor-2 B-Cell Stimulating Factor interleukin-4 MCGF 2 B-Cell Stimulation Factor-1 Interleukin-4 T-Cell Growth Factor 2 BCSF 1 IL-4 B-Cell Stimulatory Factor 1 Interleukin-4 Precursor |
| label |
Interleukin-4 |
| Legacy Concept Name |
Interleukin-4 |
| OMIM_Number |
147780 |
| Preferred_Name |
Interleukin-4 |
| prefixIRI |
Thesaurus:C20508 |
| prefLabel |
Interleukin-4 |
| Semantic_Type |
Immunologic Factor Amino Acid, Peptide, or Protein |
| Swiss_Prot |
P05112 |
| UMLS_CUI |
C1701589 |
| subClassOf |