Human Phenotype Ontology / 人类表型本体

Last uploaded: September 7, 2023
Preferred Name

Trachyonychia

Definitions

Excessive longitudinal ridging that gives the surface of the nail plate a rough appearance. It results from multiple foci of defective keratinization of the proximal nail matrix. The most common histopathologic findings of trachyonychia are spongiosis and exocytosis of inflammatory cells in the nail epithelia1. Although idiopathic trachyonychia may be much more common than reported, it may present with various associated skin or mucosal diseases including alopecia areata, lichen planus, psoriasis, and eczema. Trachyonychia predominantly occurs in children, although it can affect people of all ages. Trachyonychia can improve spontaneously but may have a chronic course exceeding 6 years and result in cosmetic handicaps.

ID

http://purl.obolibrary.org/obo/HP_0030804

comment

The most common histopathologic findings of trachyonychia are spongiosis and exocytosis of inflammatory cells in the nail epithelia1. Although idiopathic trachyonychia may be much more common than reported, it may present with various associated skin or mucosal diseases including alopecia areata, lichen planus, psoriasis, and eczema. Trachyonychia predominantly occurs in children, although it can affect people of all ages. Trachyonychia can improve spontaneously but may have a chronic course exceeding 6 years and result in cosmetic handicaps.

database_cross_reference

SNOMEDCT_US:69192004

UMLS:C0546956

definition

Excessive longitudinal ridging that gives the surface of the nail plate a rough appearance. It results from multiple foci of defective keratinization of the proximal nail matrix.

has_obo_namespace

human_phenotype

id

HP:0030804

label

Trachyonychia

notation

HP:0030804

prefLabel

Trachyonychia

treeView

http://purl.obolibrary.org/obo/HP_0002164

subClassOf

http://purl.obolibrary.org/obo/HP_0002164

Delete Subject Author Type Created
No notes to display
Create New Mapping

Delete Mapping To Ontology Source
http://purl.bioontology.org/ontology/OMIM/MTHU069754 Online Mendelian Inheritance in Man / 在线人类孟德尔遗传数据库 LOOM