loading...| Preferred Name |
Tumor Necrosis Factor Ligand Superfamily Member 15 |
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C18289 |
| code |
C18289 |
| DEFINITION |
Tumor necrosis factor ligand superfamily member 15 (251 aa, ~28 kDa) is encoded by the human TNFSF15 gene. This protein plays a role in both the inhibition of angiogenesis and the induction of apoptosis. |
| DesignNote |
Tumor necrosis factor ligand superfamily member 15 is a TNF-related type II transmembrane protein, with an extracellular C-terminus, a single transmembrane domain, and a short cytoplasmic tail. Soluble forms of the protein markedly reduce vascularization and inhibits the growth of aortic endothelial cells and colon carcinomas. |
| FULL_SYN |
TNF Superfamily Ligand TL1A Vascular Endothelial Growth Inhibitor TNFSF15 VEGI Tumor Necrosis Factor Ligand Superfamily Member 15 TNF Ligand-Related Molecule 1 |
| label |
Tumor Necrosis Factor Ligand Superfamily Member 15 |
| Legacy Concept Name |
VEG_Inhibitor |
| OMIM_Number |
604052 |
| Preferred_Name |
Tumor Necrosis Factor Ligand Superfamily Member 15 |
| prefixIRI |
Thesaurus:C18289 |
| prefLabel |
Tumor Necrosis Factor Ligand Superfamily Member 15 |
| Semantic_Type |
Amino Acid, Peptide, or Protein |
| Swiss_Prot |
O95150 |
| UMLS_CUI |
C0762871 |
| subClassOf |