loading...| Preferred Name |
Anaplastic Large Cell Lymphoma |
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C3720 |
| ALT_DEFINITION |
An aggressive (fast-growing) type of non-Hodgkin lymphoma that is usually of the T-cell type. The cancer cells express a marker called CD30 or Ki-1 on the surface, and may appear in the lymph nodes, skin, bones, soft tissues, lungs, or liver. |
| code |
C3720 |
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C126659 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C168661 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C158520 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C168655 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C177537 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C168657 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156966 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157711 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C118168 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C192842 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C165258 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156952 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C168662 |
| Contributing_Source |
CPTAC CTRP GDC FDA Cellosaurus |
| DEFINITION |
A peripheral (mature) T-cell lymphoma, consisting of usually large anaplastic, CD30 positive cells. The majority of cases are positive for the anaplastic large cell lymphoma (ALK) protein. The most frequently seen genetic alteration is a t(2;5) translocation. Majority of patients present with advanced disease. The most important prognostic indicator is ALK positivity, which has been associated with a favorable prognosis. (WHO, 2001) |
| Display_Name |
Anaplastic Large Cell Lymphoma |
| FULL_SYN |
Anaplastic Large Cell Lymphoma anaplastic large cell lymphoma Anaplastic large cell lymphoma, CD30+ Ki-1 Lymphoma NHL, anaplastic large cell lymphoma CD30 Positive Anaplastic Large Cell Lymphoma ALCL Ki-1+ ALCL Anaplastic large cell lymphoma, NOS Ki-1+ Anaplastic Large Cell Lymphoma |
| ICD-O-3_Code |
9714/3 |
| Is_Value_For_GDC_Property |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C177615 |
| label |
Anaplastic Large Cell Lymphoma |
| Legacy Concept Name |
Anaplastic_Large_Cell_Lymphoma |
| Maps_To |
Anaplastic large cell lymphoma involving lymph nodes of head, face, and neck Anaplastic large cell lymphoma, T-cell and Null-cell type Anaplastic large cell lymphoma, unspecified site, extranodal and solid organ sites 9714/3 Anaplastic large cell lymphoma Anaplastic large cell lymphoma, CD30+ Anaplastic large cell lymphoma involving lymph nodes of multiple sites NHL, anaplastic large cell lymphoma Anaplastic large cell lymphoma, T cell and Null cell type Large cell (Ki-1+) lymphoma Anaplastic large cell lymphoma, NOS |
| Neoplastic_Status |
Malignant |
| Preferred_Name |
Anaplastic Large Cell Lymphoma |
| prefixIRI |
Thesaurus:C3720 |
| prefLabel |
Anaplastic Large Cell Lymphoma |
| Semantic_Type |
Neoplastic Process |
| UMLS_CUI |
C0206180 |
| subClassOf |